Clinical neuroscience of addiction

Understanding
addiction.
Advancing treatment.

We combine human neuroscience, brain imaging, and clinical trials to understand addiction and develop better treatments.

Explore Our Research →Meet the Team

Illustrative visualization of neural pathways in a human brain

Our research

From brain circuits
to better treatments

We use human neuroscience, neuroimaging, and clinical research to understand the brain mechanisms of addiction and to develop more effective treatments.

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Clinical Trials

Developing and testing novel treatments for substance use disorders.

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Brain Imaging

Mapping brain circuits involved in addiction and recovery.

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Drug Reward

Understanding why drugs are rewarding and how responses vary across individuals.

Our mission

Translational neuroscience for real-world impact.

The Manza Lab conducts human research to understand the brain mechanisms of addiction and to develop, test, and implement better treatments. We integrate clinical trials, neuroimaging, and experimental approaches to advance science and improve lives.

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◎ Human neuroscience

♧ Clinical research

⌘ Brain imaging

✦ Treatment development

Featured project

Can ketamine improve opioid addiction treatment?

We are investigating whether ketamine can reduce opioid craving among people receiving methadone treatment. This ongoing clinical study explores a promising approach to improving outcomes in opioid use disorder.

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Featured publications